Curriculum Vitae

Prof. JanHasker G. Jonkman, Ph.D., F.C.P., F.R.Q.A., R.Ph.
 
Experience  
General:
     
 
Originally trained as a pharmacist and as bioanalytical scientist Prof.Dr. Jonkman gained extensive knowledge and experience over the years in clinical pharmacology (especially pharmacokinetics/dynamics and –genetics).
After his scientific training at the University of Groningen (The Netherlands) he was international visiting scientist at the University of California, San Francisco (U.S.A.) and at Food and Drug Administration, Washington D.C. (U.S.A.).
During the past 30 years he performed/supervised over 1,000 Phase I and Phase II clinical studies and 1,250 bioanalytical projects both in the academic and governmental environment and also in independent contact research organisations working in close cooperation with pharmaceutical companies. He was an author or co-author of over 280 publications and gave over 125 lectures on national and international conferences.
More recently he specialised in methodology within clinical pharmacology and especially in all aspects of quality management of drug research including GCP en GLP.

He is acknowledged as “Fellow in Clinical Pharmacology” both by the Dutch Association for Clinical Pharmacology and Biopharmaceutics and the American College of Clinical Pharmacology. He is also awarded as “Fellow” of the American Association of Pharmaceutical Scientists.
Furthermore he is acknowledged as “Fellow in Research Quality Assurance” by the British Association of Research Quality Assurance.

In addition to his scientific experience he also has extensive business experience, both in setting up new companies as well as running medium sized commercial organisations.
He was awarded with the King William I Award for national young entrepreneur of the year (1993) and was acknowledged with regional awards for entrepreneurship in 1995 and 1998.
 
Specific:
     
2004 - Date
 
Independent consultant in the field of (bio-)medical and pharmaceutical sciences and business issues.
Founder and CEO of PharmAdvices B.V. (Drug Development Consultancy)
 
1996 - 2011
 
Professor Quality Management in Drug Research and Manufacturing, School of Pharmacy, University of Groningen, The Netherlands
 
August 2000 - June 2002
 
Senior Director, Institute of Clinical Pharmacology, PAREXEL GmbH, Berlin
 
February 2000 - October 2003
 
Vice President Scientific Relations, Clinical Pharmacology International, PAREXEL GmbH, Berlin
 
1984 - 2000
 
Founder, President & CEO and Executive Director Scientific Affairs of Pharma
Bio-Research International B.V., Zuidlaren/Assen, The Netherlands
 
1982 - 1983
 
“International Visiting Scientist” (biopharmaceutics), Food and Drug Administration, Biopharmaceutics Laboratory (US Government), Washington DC, USA
 
1979 - 1981
 
“International Visiting Scientist” (bioanalysis and pharmacokinetics) at the University
of California, School of Pharmacy, Department of Pharmacy, San Francisco, USA
 
1977 - 1991
 
On a part-time basis, senior research scientist at the School of Pharmacy, University
of Groningen, The Netherlands
 
1977 - 1984
 
Owner/Director of “Karsten Pharmacy”, Assen, The Netherlands
 
1971 - 1977
 
Senior Research Scientist, University of Groningen, The Netherlands
 
1963 - 1971
 
Student-Assistant in Physiology and Analytical Chemistry, University of Groningen,
The Netherlands

 
 
EDUCATION:
     
1971 - 1977
 
Research for Ph.D. – thesis: “Thiazinamium Methylsulphate, Bioanalysis and Pharmacokinetics”
 
1963 - 1971
 
Pharmacist Certification R.Ph. – University of Groningen, The Netherlands, School of Pharmacy
 
1958 - 1963
 
Secondary School (Dutch System: HBS-B), Oosterwolde, The Netherlands, Graduation June 21, 1963
 
 
PRACTICAL TRAINING:
     
1975 - 1976
 
Training in Autoradiography and Pharmacokinetics at the University of Nijmegen,
The Netherlands
 
1974
 
Training in Ion Pair Extraction at the Laboratory of Pharmaceutical-Analytical Chemistry, University of Uppsala, Uppsala, Sweden
 
1972
 
Training in Pharmacokinetics, Chelsea College, London, United Kingdom
 
 
CERTIFICATIONS:
     
1994
 
Course on Good Laboratory Practices (International Standards and Quality Assurance), Zeegse, The Netherlands
 
1993
 
Course on Good Clinical Practices (International Standards and Quality Assurance), Zeegse, The Netherlands
 
1992
 
Course on Clinical Pharmacology, University Hospital Groningen, The Netherlands
 
1991
 
Boerhaave Course “Medicamenteuze therapie in 2000”, University of Leiden, The Netherlands
 
 
MEMBERSHIPS/FELLOWSHIPS OF SCIENTIFIC SOCIETIES:
     
 


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Member (and/or Fellow) of over 30 societies/associations of scientific professions, among them:

NVKFB (Nederlandse Vereniging voor Klinische Farmacologie en Biofarmacie; Dutch Society for Clinical Pharmacology and Biopharmaceutics)
NVFW (Nederlandse Vereniging voor Farmaceutische Wetenschappen; Dutch Association for Pharmaceutical Sciences)
NVFG (Nederlandse Vereniging van Farmaceutische Geneeskundigen; Dutch Association for Pharmaceutical Physicians)
DARQA (Dutch Association of Research Quality Assurance)
BARQA (British Association of Research Quality Assurance)
BPS (British Pharmacological Society (+ Section Clinical Pharmacology))
AAPS (American Association of Pharmaceutical Scientists)
ACS (American Chemical Society (Division of Analytical Chemistry))
ACCP (American College of Clinical Pharmacology)
DIA (Drug Information Association)
AGAH (Arbeidsgemeinschaft für Angewandte Humanpharmakologie)
DG Pharm Med (Deutsche Gesellschaft für Pharmazeutische Medizin e.V.; German Association for Pharmaceutical Medicine)
EUFEPS (European Federation for Pharmaceutical Sciences)
EFGCP (European Forum for Good Clinical Practice)
ACRP (Association of Clinical Research Professionals)

 
 
BOARD MEMBERSHIPS:      
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Added Member of the Board of the European Forum for Good Clinical Practice, Brussels
Member of the Management-Committee at the COST-B25 Project (European Union, Brussels)
Former Member of the Management-Committee at the COST-B15 Project (European Union, Brussels)
Former Member of the Management-Committee at the COST-B1 Project “The Role of Metabolic and Kinetic Studies in Drug Research and Development”, Commission of the European Community, Brussels
Former Member of the Executive Committee (and co-founder) of the Association of Independent Clinical Research Contractors (AICRC)
Former Member of the “Committee for Pharmaceutical and Biomedical Analysis” of the Koninklijke Nederlandse Chemische Vereniging (Royal Dutch Chemical Society)
Former Member of the working group “Quality Assurance in Pharmaceutical Analysis”
Former Member of the “Committee on Doping” (expert on bioanalysis; National Institute for Sport and Health)
Former Member (Chairman) of the “Laboratory Committee” of the Koninklijke Nederlandse Maatschappij ter Bevordering der Pharmacie (Royal Dutch Association for Advancement of Pharmacy)
Former Member of the “Committee for National Monographies” (The Dutch Pharmacopoeia Commission)
Former Member of the Board of the “Centre for Innovation Drenthe” (Innovatie Centrum Drenthe)

 

 
SPECIAL APPOINTMENTS/AWARDS
     
 

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Appointed as “Expert Pharmacology/Toxicology” by the French Government on July 08, 1983 (Appointment published in “Bulletin Officiel du Ministère des Affaires Sociales et de la Solidarité Nationale” no. 31, September 02, 1983)

Appointed as “Expert Analyse” by the French Government on June 03, 1987

Appointed as “Biomedical Scientist/Toxicologist” by the ”Stichting voor Opleiding tot Medisch Biologisch Wetenschappelijk Onderzoeker” (Society for Training of Medical Biological Scientific Researcher), The Netherlands, March 18, 1988

Acknowledged as “Fellow” of the American College of Clinical Pharmacology, June 09, 1989

Acknowledged as honorary member of “Pharmaciae Sacrum”, the association of pharmacy students at the University of Groningen on October 13, 1992

Appointed as Scientific Adviser of the Groningen Institute for Drug Studies, University of Groningen, 1993

Appointed as “Referee” for the Ph.D.-thesis of Dr. J. Wieling entitled: “Liquid-liquid extractions of drugs from biological fluids: robotization and optimization”, University of Groningen, May 03, 1993

Acknowledged as honorary member (“Fellow”) of the Nederlandse Vereniging voor Klinische Farmacologie en Biofarmacie (Dutch Society for Clinical Pharmacology and Biopharmaceutics), 1993

King William I Award 1993. This plaque is awarded biannually to a company which has contributed in an exceptional degree to the economic activity of The Netherlands as a source of employment and welfare, and which not only conducts its affairs in accordance with the requirements of sound business management, but also has distinguished itself by outstanding achievements in a specific area. The prestigious plaque was presented to Dr. J.H.G. Jonkman on June 01, 1993, by his Royal Highness Prince Claus of
The Netherlands in the “Ridderzaal” in The Hague, The Netherlands

Acknowledged as honorary member (“Fellow”) of the American Association of Pharmaceutical Scientists (AAPS), 1995

Elected as “Entrepeneur of the year 1995 - Drenthe”

Awarded with the “1998 Wubbo Ockels Award of the City of Groningen”. The prize is awarded biannually (for the first time to Prof. W.J. Ockels in 1985) for an extraordinary achievement in the field of natural science or technology. Prof. J.H.G. Jonkman was awarded the prize for “his significant contribution to the professionalization of scientific research aimed at the development of new drugs”, according to the jury’s report. The 1998 Wubbo Ockels Award was presented by Mr. J. Wallage, Mayor of the city of Groningen. The title of Prof. Jonkman’s speech of thanks was: Pharmacogenetic aspects of drug development and pharmacotherapy (“on genotyping and phenotyping”)

Acknowledged as “Fellow” of the British Association of Research Quality Assurance (BARQA), 2002

 

 
REFEREESHIP:
     
   
Acts frequently as a referee for several scientific journals such as Pharmaceutical Research, Journal of Pharmaceutical Sciences, Clinical Pharmacokinetics, Journal of Chromatography B-Biomedical Applications, European Respiratory Journal, Biopharmaceutics and Drug Disposition, European Journal of Epidemiology, Pharmacology and Toxicology and Pharmacy World & Sciences (Pharmaceutisch Weekblad, Scientific Edition).
 

 
OTHERS:
     
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Treasurer Rotary Club Assen (2004 – 2005)
President Rotary Club Assen (2006 – 2007)
President (and founder) of the "Stichting Certificering Klinisch Wetenschappelijk Onderzoeker" (Foundation for Certification of Clinical Researchers)